Cowboys vs. Giants: Where to watch NFL Week 2, betting odds, prediction for Russell Wilson vs. Dak Prescott

 The Dallas Cowboys welcome the New York Giants to AT&T Stadium for an NFL Week 2 rivalry showdown. These teams made up the bottom of the NFC East last season, with the Cowboys finishing 7-10 and New York finishing 3-14. The Cowboys opened their 2025 campaign with a hard-fought battle against the Eagles in Philadelphia but fell short, 24-20. Meanwhile, the Giants stumbled in Russell Wilson's debut for the team, falling 21-6 to the Washington Commanders. 

Kickoff from AT&T Stadium is set for 1 p.m. ET. Dallas has won eight straight meetings with New York and is a 5.5-point favorite in the latest Giants vs. Cowboys odds from SportsLine consensus, while the over/under for total points scored is 44.5. The Cowboys are -245 money line favorites (risk $245 to win $100), and Dak Prescott's over/under for total passing yards is 250.5. Before making any Cowboys vs. Giants picks, make sure you check out the picks from the SportsLine Projection Model.

Click here to bet Giants vs. Cowboys at DraftKings Sportsbook, where new users get $200 in bonus bets and over  Sunday

When: Sunday, Sept. 14

Time: 1 p.m. ET
TV: FOX
Stream: Fubo
Follow along: CBS Sports App

Cowboys vs. Giants betting preview

Odds: Cowboys -5.5, over/under 44.5

Neither team did particularly well covering the spread last year, with Dallas finishing 7-10 ATS in 2024 and New York finishing 5-12 ATS. However, the Cowboys covered the spread in both head-to-head meetings. Plus, they are already off to a better start in 2025 after hanging tough against the defending Super Bowl champions. Dak Prescott was held to 188 passing yards and no touchdowns in that game -- it didn't help that CeeDee Lamb dropped multiple passes -- but the Cowboys defense leveled the playing field by keeping Jalen Hurts from hitting the end zone as well.

The same can't be said for the Giants, who looked overwhelmed by Jayden Daniels and the Commanders. Wilson looked disjointed from Malik Nabers and the receiving corps as he completed 17 of 37 pass attempts, and New York's defense tied for second-most yards allowed in Week 1 at 432. (The other team was the Buffalo Bills, who were in an offensive track meet with the Baltimore Ravens on Sunday night.)